GLP-1 Dosing & Administration Guides
Educational dosing schedules and injection guides drawn from FDA labeling for the brand-name GLP-1 products. Dose titration, administration technique, and missed-dose handling.
Dosing Guides by Brand
Once weekly
Ozempic Dosing
Semaglutide · Injectable pen
View guide
Once weekly
Wegovy Dosing
Semaglutide · Injectable pen
View guide
Once weekly
Mounjaro Dosing
Tirzepatide · Injectable pen
View guide
Once weekly
Zepbound Dosing
Tirzepatide · Injectable pen
View guide
Once daily
Rybelsus Dosing
Semaglutide · Oral tablet
View guide
Once daily
Oral Wegovy Dosing
Semaglutide · Oral tablet
View guide
Frequently Asked Questions
How often are GLP-1 medications injected?
Most GLP-1 medications are once-weekly subcutaneous injections. This includes the FDA-approved brand-name semaglutide products Ozempic® and Wegovy®, as well as the brand-name tirzepatide products Mounjaro® and Zepbound®. Rybelsus® is a daily oral semaglutide tablet.
What is dose titration?
Dose titration means starting at a low dose and gradually increasing over several weeks. The FDA-approved labeling for the brand-name GLP-1 products specifies titration schedules of 4-8 weeks per step to allow the body to adjust and reduce side effects.
Where are GLP-1 injections given?
Subcutaneously (under the skin) in the abdomen, thigh, or upper arm. Injection sites should be rotated each week.
What should I do if I miss a dose?
Per FDA labeling for the brand-name once-weekly GLP-1 products, if a dose is missed and fewer than 5 days have passed, take it as soon as possible. If more than 5 days, skip the missed dose and resume the regular schedule.
How is GLP-1 medication stored?
Per the brand-name product labeling, unused pens are refrigerated at 36-46°F (2-8°C). Once in use, they may be stored at room temperature (up to 86°F/30°C) for up to 56 days. Medication should not be frozen.