Ozempic (semaglutide) is a once-weekly injectable GLP-1 receptor agonist delivered via a pre-filled, single-patient-use pen. Your Weight Method provider will guide you through a gradual dose escalation over 8+ weeks to minimize side effects and optimize results. The starting dose is 0.25 mg weekly, increasing to a maintenance dose of 1 mg or 2 mg depending on your individual response and treatment goals.
Ozempic dosing starts at a low dose and gradually increases over 16-20 weeks to minimize side effects. Weight Method providers create personalized titration schedules. Treatment starts at $297/month with direct-to-door shipping.
Key Fact
Ozempic dosing: start at 0.25mg weekly for 4 weeks, then 0.5mg for 4 weeks, increasing to 1mg and optionally 2mg. Administer once weekly via pre-filled pen, same day each week, any time of day. Rotate injection sites (abdomen, thigh, upper arm).
Source: Ozempic FDA prescribing information
Ozempic follows a 3-step escalation: 0.25mg weekly for 4 weeks, then 0.5mg for 4 weeks, then 1mg maintenance — with optional increase to 2mg for greater effect.
Begin with 0.25 mg once weekly for the first 4 weeks, then increase to 0.5 mg once weekly for the next 4 weeks, followed by 1 mg once weekly as your maintenance dose. If additional glycemic or weight control is needed, your Weight Method provider may increase the dose to 2 mg weekly. Choose the same day each week for your injection — you can change your injection day as long as there are at least 2 days (48 hours) between doses.
Inject subcutaneously once weekly in the abdomen, thigh, or upper arm. Rotate injection sites each week. Attach a new needle, dial the dose, and hold for 6 seconds.
Inject Ozempic subcutaneously into the abdomen, thigh, or upper arm. Rotate your injection site each week to reduce the risk of skin irritation or lipodystrophy. Clean the area with an alcohol swab before injecting. Attach a new needle for each injection, dial your prescribed dose on the pen, insert the needle at a 90-degree angle, and press the dose button. Hold the button for 6 seconds to ensure full delivery.
If less than 5 days late, take the missed dose immediately. If more than 5 days have passed, skip it and resume your regular schedule the following week.
If you miss a dose, take it as soon as possible within 5 days of the missed day. If more than 5 days have passed, skip the missed dose and take your next dose on the regularly scheduled day. Do not take two doses within 2 days of each other to make up for a missed injection. Contact your Weight Method care team if you miss multiple doses, as your escalation schedule may need adjustment.
Store unused pens in the refrigerator at 36-46°F (2-8°C). Once in use, can be kept at room temperature below 86°F for up to 56 days. Do not freeze.
Store unused Ozempic pens in the refrigerator at 36-46 degrees F (2-8 degrees C). Do not freeze. After first use, the pen can be kept at room temperature (up to 86 degrees F / 30 degrees C) or refrigerated for up to 56 days. Keep the pen cap on when not in use to protect from light. Discard the pen after 56 days of first use, even if medication remains.
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